BIO Mary Nash Stoddard on Twitter

PRESENTING: MARY NASH STODDARD - Co-Founder of the massive international anti-aspartame movement in the mid 1980's, following the brain tumor death of her forty two year old husband, Mike. Ms. Stoddard suffered a life threatening aspartame-related blood disorder in 1985, whereupon, The NutraSweet Co. offered her an all-expense paid vacation for two anywhere in the world, if she would agree to be tested by their doctors. She declined, with the blessing of her doctor, and the rest is history. She has conducted multi-national lecture tours and is a popular visiting professor at colleges, universities and medical schools. "Deadly Deception - Story of Aspartame" is a toxicology sourcebook, edited by Ms. Stoddard, documenting the harmful effects of the world's most toxic artificial sweetener. The companion one hour "Deadly Deception" video is further documentation - taped at a prestigious scientific conference. Stoddard's efforts, over more than two decades, led to the present rejection of the sweetener by many of the food and beverage giants of industry, as they rush to distance themselves from the liabilities associated with use of a neuro-toxic substance in their products. She has testified in court as an Expert Medical Witness and like her counterpart, Erin Brokovitch, helped with a number of lawsuits on behalf of consumers. Her powerful message has reached millions around the world through the airwaves on radio and television, in print and through popular personal appearances. Honors, Awards, Societies: • Expert Medical Witness [1992-present] * Guest Presenter Gulf War Veterans Annual Conference - [Las Vegas 1999] * Visiting Professor: U. T. Southwestern Medical School [1997] * Visiting Professor: American University School of Journalism [1999] * Visiting Professor: University of North Texas at Denton Dept. of Science [1990 and 2005] • Visiting Professor: University of Houston Bioneers Conference [2006] * Invited speaker: Hebrew Univ. Jerusalem - [1997] * Keynote speech: Mexican Government's Annual Conference on Sweeteners [1999] * Appointed Judge - State of Texas [1977-1984] * Broadcast Journalist - [1965-present] * President's Council on Food Safety - [1998-1999] * International Lecture Tours - [1996-present] * Testimony Senate Committee Hearing on Safety of Aspartame - Washington [1987] * Panelist at National News Conference Announcing Dr. John Olney's Brain Tumor/Aspartame Connection - Washington D.C. [1998] * Inducted Member Texas Radio Hall of Fame [2002-present] Representative of the Texas Rice Growers Association [Miss Rice] Board member: Irving Symphony Orchestra Board Member: Irving Community Theater Founding Board Member Radio Station KNON [public radio], Dallas Charter member City of Dallas Citizens Safety Committee Board Member Dallas Mayor’s Fee Task Force Vice President Operation Get Involved, [liaison committee of the D.P.D.] Board member Dallas Homeowners League President Save Open Space Texas Steering Committee Presidential Election Award for Public Service - Mexican Government State of Texas Board of Adjustment

Wednesday, September 12, 2012

ASPARTAME BRAIN DAMAGE IN PKU AND OTHERS - WASHINGTON POST ARTICLE

The Washington Post & The Daily Record, 1987 New fuel for NutraSweet debate Researchers clash over findings on safety of sugar substitute

By SANDY ROVNER-The Washington Post Daily Record Newspaper Monday June 1, 1987

WASHINGTON˜A series of scientific studies in this country and abroad is stirring new concern among some scientists over the safety of aspartame, the immensely popular sugar substitute marketed as NutraSweet. But a spokesman for the company cited the same studies as evidence that the product is safe. An estimated 4,000 tons of the sweetener, some 200 times sweeter than sugar, is consumed every year, and sales are estimated now at more than $l billion annually and increasing rapidly. 

Last month, at a scientific conference that was closed to the press, researchers reported that heavy aspartame use appears to increase migraine headaches and seizures in susceptible individuals, cause changes in electroencephalogram (EEG) readings and may even be related to birth defects and retardation. However, Dr. Frank Kotsonis, head of research for the NutraSweet Co., said he found the studies either seriously flawed or used to support unwarranted conclusions. And Dr. Bennett A. Shaywitz, chief of pediatric neurology at Yale University, said he found the ambience at the conference "similar to past meetings on the usefulness of the Feingold diet as a cure for hyperactive children. "There was a fanaticism there that made me very uncomfortable." Shaywitz is conducting a study of aspartame in seizure-prone children between the ages of 5 and 12 but so far has been unable to demonstrate any adverse effects from the sweetener. G D Searle, which manufactures aspartame, and the NutraSweet Co, which markets it have maintained that the substance's 1981 Food and Drug Administration approval came with more safety studies than any product in history.

Some researchers believe, however, that because the tests were looking for acute deleterious effects they missed the more subtle effects that may occur over a long period of time. Dr. Paul Spiers, a clinical neuropsychologist of the Behavioral Neurology Unit and the Harvard Medical School's Comprehensive Epilepsy Center at Beth Israel Hospital in Boston, presented at the meeting some preliminary evidence that use of aspartame over a period of time might affect intellectual functioning in normal users. In an interview Spiers said the findings had been something of an accident. He had been planning to study the effects of aspartame on individuals who reported that they had suffered seizures after ingesting aspartame. However, he was first ethically bound to run the tests on normal control subjects to confirm their safety. "For that reason," he said, "we went out and selected people specifically who had a history of using NutraSweet products and were not aware of it having any adverse effects on them. We picked normal neurological histories, no history of psychiatric illness and no physical problem˜nothing, in fact, that would suggest that we would expect to have problems.

The group was given aspartame capsules up to the FDA's maximum allowable limit˜50 milligrams per Kilogram of weight˜three times a day for 12 days. Unexpectedly, the researchers began to find "cognitive deficits" in some of the neuropsychological tests then done on the group. Among the tests was a sophisticated computer test called "Think Fast," which requires comparisons, copying and recall of patterns of blocks and sequences of letters. Spiers describes it as "quite demanding and self-paced, becoming increasingly difficult. Normally when a test like this is repeated, subjects tend to improve in their performance as they learn how the test is done." Nevertheless the subjects on aspartame failed to improve and some of them frankly showed a reverse pattern where their performance got worse." 

Although he was admittedly dealing with only a few subjects and checking performances on only a small number of the tests that were administered, Spiers believes the findings are important A second group of volunteers who were given a placebo instead of aspartame showed none of the problems manifested by the aspartame group. The computer test and others measured functioning of the brain's frontal lobe, Spiers said, "simulating what the brain does in everyday life.""We are wondering whether in fact this substance may be capable of having a subtle effect on cognitive functioning that people may not necessarily be aware of. Think of the implications, for example, on an average college student who starts consuming a liter of this stuff during examination period, and it may in fact he interfering with his concentration and attention skills." Said Spiers; "This kind of neuro-psychological cognitive examination has never been used to investigate the effects of new drugs of any kind. 

Now we have food additives that are more like drugs than foods are introduced into the dietary chain but have direct effects on the brain's neurotransmitter system. But because the chemical industry is 20 years ahead of the regulators, thus far no one has attempted to apply more sophisticated methods of testing brain functions to these problems. 

"NutraSweet's principal ingredient is an amino acid called phenylalanlne (PHE), which is found, along with other amino acids, in protein. There is a genetic disorder called phenylketonuria (PKU) in which the ability to normally process the amino acid is impaired. Without careful dietary restriction of protein, PKU babies may suffer severe, irreversible mental retardation. All products containing NutraSweet must warn against its use where PKU exists. 

Now, however, specialists and researchers believe that there may be many more people who carry the gene for PKU but show no symptoms who, however, may be unable to deal with the extra load of PHE that comes from using products containing NutraSweet. Dr. Reuben Matalon, a geneticist and pediatrician at the University of Illinois warned those at the conference that perhaps millions of PKU carriers are at risk of varying reactions to aspartame, as are the fetuses of pregnant carriers.Another major study presented at the conference suggested that the use of aspartame could increase the frequency of migraine headache fourfold. 

However, both Kotsonis and Shaywitz said they believed the study was poorly conducted. They cited another study done at Duke University (at Duke's G.D. Searle Ctr.), now awaiting publication that found no link between migraines and NutraSweet. (Funded by manufacturer.) Dr. Richard J. Wurtman, neurophysiologist at the Massachusetts Institute of Technology and one of the organizers of the conference, called for more studies of the 3,000 people who have complained of reactions to NutraSweet. "Except for the migraine study, which is preliminary, at this point we cannot say aspartame is responsible for all those anecdotes. Still, given the basic science findings and the anecdotes," Wurtman said, "the index of suspicion is high." Said Spiers: "I think it is in everyone's interest to do good research on this. 

It may turn out that it is just a labeling issue, that the warning needs to be broader. People still smoke, but they smoke knowing the consequences. The difference here is that people have not understood the consequences " "How many people even know that the FDA has attached a limit to aspartame consumption?" asked James Wagoner. Legislative aide to Sen. Howard Metzenbaum, (Ohio). (Bowing to industry pressure, in a previously unprecented move, FDA also doubled their normal Allowed Daily Intake for aspartame.)

Metzenbaum has introduced legislation requiring that labeling include information about how much NutraSweet is contained in a serving of a given product. The FDA‚s limit of 50 milligrams per kilogram of body weight translates to about four liters of a diet drink for an adult but only to about three cans for a child who weighs about 30 pounds."Americans,'' Wagoner said at the conference, "drink over 20 billion cans of diet soft drinks a year. And that doesn't count the gum, pudding, breakfast cereal, chewable vitamins, tooth paste, juices, frozen pops - all sweetened. with NutraSweet 

"Researchers reported last month that that heavy aspartame use appears to increase migraine headaches and seizures in susceptible individuals cause changes in electroencephalogram (EEG) readings and may even be related to birth defects and retardation.'We are wondering whether, in fact, this substance may be capable of having a subtle effect on cognitive functioning that people may not necessarily be aware of. Think of the implications, for example, on an average college student who starts consuming a liter of this stuff during examination period, and it may in fact be Interfering with his concentration and attention skills. Dr. Paul Spiers



posted by Mary Nash Stoddard on March, 17