DEADLY HEART ADVERSE REACTIONS TO ASPARTAME SWEETENERS

HEART SYMPTOMS LINKED TO ASPARTAME USE
Mon Jul 23, 5:11 PM

By Sheryl Ubelacker

TORONTO (CP) - For those who drink diet pops in the belief that sugar-free beverages are healthier than regular soft drinks, new research suggests they should think again.

A huge U.S. study of middle-aged adults has found that drinking more than one soft drink a day - even a sugar-free diet brand - may be associated with an elevated risk for metabolic syndrome, a cluster of factors that boosts the chance of having a heart attack or stroke and developing diabetes.

Officials of a leading aspartame awareness group, Aspartame Consumer Safety Network, reported today to confirm the findings of the Framingham Heart Study

"We found that one or more sodas per day increases your risk of new-onset metabolic syndrome by about 45 per cent, and it did not seem to matter if it was regular or diet," Dr. Ramachandran Vasan, senior investigator for the Framingham Heart Study, said Monday from Boston.

"That for me is striking."

Metabolic syndrome is associated with five specific health indicators: excess abdominal fat; high blood sugar; high triglycerides; low levels of the good cholesterol HDL; and high blood pressure.

"And other than high blood pressure, the other four . . . all were associated with drinking one or more sodas per day," said Vasan, a professor of medicine at Boston University.

Having metabolic syndrome is known to double the risk of heart attack and stroke, as well as boosting the risk of diabetes.

The study included nearly 9,000 observations of middle-aged men and women over four years at three different times. The study looked at how many 355-millilitre cans of cola or other soft drinks a participant consumed each day.

The researchers found that compared to those who drank less than one can per day, subjects who downed one or more soft drinks daily had a:

-31 per cent greater risk of becoming obese (with a body mass index of 30 or more).

-30 per cent increased risk of adding on belly fat.

-25 per cent higher risk of developing high blood triglycerides or high blood sugar.

-32 per cent higher risk of having low HDL levels.

But Vasan and his colleagues, whose study was published Monday in Circulation: Journal of the American Heart Association, are unsure what it is about soft drinks that ratchets up the risk of metabolic syndrome.

"We really don't know," he said. "This soda consumption may be a marker for a particular dietary pattern or lifestyle. Individuals who drink one or more sodas per day tend to be people who have greater caloric intake. They tend to have more of saturated fats and trans fats in their diet, they tend to be more sedentary, they seem to have lower consumption of fibre."

"And we tried to adjust for all of these in our analysis . . . but it's very difficult to completely adjust away lifestyle."

Dr. David Jenkins, director of the Risk Factor Modification Centre at St. Michael's Hospital in Toronto, said previous studies have suggested that diet pops did not have the same effects on weight and health as do naturally sweetened soft drinks.

"The unusual thing that needs comment is they (the study authors) say that the diet colas are the same as the calorically sweetened colas," said Jenkins. "So I think that is the piece that they've put into this puzzle . . . I think we need a lot more scrutiny of that."

Jenkins said he believes that high consumption of soft drinks likely goes along with eating a high-calorie diet.

"I think the disappointing thing is if you thought you were doing (yourself) a major service - which you always used to think - by taking diet drinks, this is not helping you," he said. "Before we were saying take the diet (drink) and you're OK. Now were saying: 'Watch it."'

The study also begs the question whether there is some ingredient in soft drinks - regular or diet - that may encourage metabolic syndrome.

But Dr. Arya Sharma, chair of cardiovascular obesity research at McMaster University, said there is nothing suggested by the authors of the study that would lead to that conclusion.

"One thing that they say and other people have said before is if you drink a lot of sweet things, then you are sort of conditioning yourself for that sweet taste," Sharma said Monday from Hamilton. "So people who drink diet pop may be eating other sweets, whether that comes in the form of dessert or other things, I don't know."

"It may be that people who are drinking diet pop - and we have this effect often with people who go on diets or when people go running or whatever - that you do a little bit of something that you think is good, and then you overcompensate by doing more of something that is bad."

"The idea could be because I'm drinking diet pap, I can afford to splurge on dessert."

Vasan said he cannot out-and-out recommend that people stop drinking soft drinks based on this study, because the findings are based on association, not clear cause and effect.

"The simple message is eat healthy, exercise regularly and everything should be done in moderation," he said. "If you're a regular soda drinker you should be aware that this study adds to the evidence that regular soda may be associated with metabolic consequences."

"If you're a diet soda drinker, stay tuned for additional research to confirm or refute these findings."


From: marystod@airmail.net
Subject: Fwd: Sudden Cardiac Death
Date: April 5, 2007 7:13:38 PM CDT

Heart Problems Associated With Aspartame/Methanol Ingestion:

Sudden Cardiac Death is not a "heart attack" or myocardial infarction caused by clogged arteries. It's an electrical problem in which the cardiac conduction system that generates the impulses regulating the heart suddenly puts out rapid or chaotic electrical impulses, or both. The heart ceases its rhythmic contractions, the brain is starved of oxygen and the victim loses consciousness in seconds.

Aspartame's biochemical route to SCD

Dr. J. Bowen believes the evidence is pointing the finger at aspartame as the toxin responsible for sudden death in many of these instances. "The combination of aspartame consumption with the stresses of strenuous athletic competition lead to activation of the shock mechanism including the elaboration of arginine vasopressin in the hypothalamus. This results in cerebral edema, cardiac congestion and pulmonary edema in combination with severe potassium wastage which is a sure ticket to sudden death, especially in the face of the many damages inflicted by aspartame.

"Aspartame is already well known for causing neuroendocrine abnormalities such as serotonin elevations and suppression in various areas of the brain. Due to its phenylalanine isolate poisoning, which depletes dopamine, and hypothalamic damage from its extreme excitotoxic effect and resultant formaldehyde/formic acid poisoning especially focused in the hypothalamus, any biochemist could verify the direct effect of aspartame poisoning in producing the fatal aberrant shock mechanism in those exposed to it. The mere occurrence of severe athletic stress does not cause this to happen all by itself," Dr. Bowen reasoned.

Indeed, only in recent history is it mentioned that people have a habit of simply "dropping dead" from routine exertion.

Aspartame triggers an irregular heart rhythm and interacts with cardiac medication. It damages the cardiac conduction system and is a direct cause of sudden death. What Dr. Bowen is saying, of course, is that it's not just hitting their hearts but their hypothalamus and neuroendocrine systems as well.

Of interest is the report from The Telegraph in the UK regarding an investigation of why children, having mild seizures that normally don't cause death, die before they can get to a hospital. Dr. Bowen responded: "Sudden death during seizures is almost always from cardiac standstill due to arrhythmias. There are several ways that aspartame can cause this damage. Aspartame and methyl alcohol poisoning are noted for damaging myocardium as well as the cardiac conduction system itself.

"This kind of damage leads to susceptibility to irregular heartbeats, or arrhythmias. The aspartame and methyl alcohol poisoning cause immense damage to the mitochondria and to MtDNA which perpetuates the mitochondria damage. The myocardium and cardiac conduction system never get to rest. They are constantly at work pumping blood, therefore they are very highly concentrated in mitochondria to accommodate the metabolic needs of this tremendous work load.

"Therefore, mitochondrial damage is more highly reflected in the heart. Damaged mitochondria produce increased amounts of free radicals and other abnormal metabolite-producing arrhythmias.

"The person using NutraSweet may have a markedly decreased intake of mineral and vitamin co-enzyme factors which also sensitizes the heart to arrhythmias. Seizures always put unusual demands on the cardiorespiratory system and seizures due to NutraSweet occur more frequently and in spite of otherwise adequate anti-seizure medication. Aspartame creates unusual medical toxicity from the anti-seizure medication.

"It should be no surprise then that people are dropping dead from this aspect of aspartame toxicity."
_________________________________________________________________________________
CDC review

In Nov. 1984 the CDC compiled a report reviewing 213 of 592 cases of aspartame complaints. Some of these included cardiac arrest, seizures, disorientation, hyperactivity, extreme numbness, excitability, memory loss, loss of depth perception, liver impairment, severe mood swings and even DEATH. Frederick L. Trowbridge added an executive summary that conflicted with the information in the report by stating that the complaints were "generally of a mild nature."

Original:

Pituitary - Markedly enlarged; slightly hyperemic.
Heart - Left Ventricle has undergone dilitation walls thin.
Lung - Right, anterior, medial and post-caval lobe have
undergone consolidation.
Testes - Marked atrophy, bilaterally.

Seminal Vesicle - Marked atrophy, bilaterally.

Thyroid - Moderately enlarged, bilaterally. A 2 mm in dia., dis-
crete, sl raised, moderately firm yellowish-grey lesion
is located in the posterior tip, bilaterally. (Thyroid
submitted in toto wrapped in a lens paper).

Heart - Wall of left ventricle thin
Brain - Marked autolysis
Pituitary - Marked autolysis
Pituitary - Marked enlargement.
Pit - appears markedly hyperemic
Heart - Left ventricle has undergone a moderate amount of dili-
tation. Wall, left ventricle is thin.

Female Rat No. F16CF (Path No. 95619)
Heart - Focal Fibrosis.
Kidney - Mild chronic nephritis.

Female Rat No. K29CF (Path No. 95631)
Heart - Focal fibrosis
Kidney - Focal calcification

Female Rat No. M4CF (Path No. 95632)
Liver - Focal hyperplasia

Female Rat No. M10CF (Path No. 95634)
Kidney - Focal calcification.
Pituitary - Adenoma
Ovary - Fibrosis and Pigmentation.

(65)

Female Rat No. M15CF (Path No. 95635)
Pituitary - Adenoma.
Ovary - Cyst.

Female Rat No. B30CF (Path No. 95801)
Kidney - Focal calcification.

Female Rat D29CF (Path No. 95803)
Urinary Bladder (1) Chronic diffuse inflammation.
(2) Diffuse mild hyperplasia.

The second phase of the review consisted of the microscopic examination of
all tissues from the high dose females - a total of 36 animals. The
inconsistencies are listed below:

Female Rat No. B14HF (Path. No. 95657)
Eye was reported as not examined but eye was present and
normal.

Female Rat No. F25HF (Path. No. 95823)
Urinary Bladder - Mild diffuse hyperplasia.

Female Rat No. H7HF (Path No. 95623)
Ovary - Neoplasm - probably granulosa cell tumor.

Female Rat No. H9HF (Path No. 95665)
Heart - Focal fibrosis.
Urinary Bladder - Mild focal hyperplasia.

Female Rat No. H15HF (Path No. 95665)
Lymph Node - The diagnosis of lymphoma, benign, was present on
the Searle microscopic report. According to Dr. Frith, lymphoma
is generally not considered to be benign and he would diagnose
lympphosarcoma.

Female Rat NO. H18HF (Path No. 95667)
Pituitary - Adenoma.
Brain - Mild bilateral hydrocephalus.

Female Rat No. K18HF (Path No. 95824)
Pituitary - Adenoma

Female Rat No. K24HF (Path. No. 95671)
Mass noted grossly - nothing consistent with mass reported
microscopically.

(66)

Female Rat No. - M2HF (Path. No. 95672)
Uterus - Chronic mild endometritis.

Female Rat No. M30HF (Path. No. 95343)
Kidney - Focal calcification.
Uterus - Chronic mild endometritis.

Female Rat No. M30HF (Path. No. 95675)
Pancreas - Focal hyperplasia.

The third phase of this review consisted of microscopic verification of
all masses reported grossly at necropsy from all female animals not
examined in phases 1 and 2 and included a total of 73 animals. The
inconsistencies are listed below:

Female Rat No. D10Lf (Path No. 92521)
Subcutaneous mass was diagnosed as an angiofibroma on Searle
report. The lesion is more consistent with an angiosarcoma.

Female Rat No. K9MF (Path. No. 95707)
Uterus - Polyp.

Female Rat No. M1LF (Path. No. 95844)
Tissue mass seen grossly was reported as missing and not
available for microscopic examination. The tissue was
present and was a mammary fibroadenoma.

In summary, Dr. Frith reviewed:

1) All 36 high dose females (all slides) including 3 that had
been excluded from the study due to autolysis.

2) 36 (one-half) of the control females (all slides) including
1 animal that had been excluded from the study due to auto-
lysis.

3) Remaining 73 female animals with grossly observed masses.
(sufficient slides were reviewed to substantiate the masses)

4) 5 additional animals selected by the investigators (A1HM,
A9HM, A29HM, C2CM, C24HM).

(67)

The slides reviewed in the first two categories above constituted 20% of
the total animals on the study. Dr. Frith reviewed these slides blindly
and then compared his findings with the Searle microscopic reports.
According to Dr. Frith, his findings were in agreement with those of
SEarle, for the most part. In his opinion, some of the lesions that he
reported as inconsistencies were small, and might be considered
insignificant by some pathologists. Dr. Frith did feel, however, that the
ovarian neoplasms (animals H10CF, H19CF, and H7HP, and chronic cystitis
and diffuse hyperplasia (animal D29CF) should have been reported.

Dr. Frith also considered two other discrepancies to be significant. They
were:

1) The reporting of a mass (by Searle) as missing which was
actually present (MlLF).

2) The finding of a polyp of the uterus which was not diagnosed
by Searle (K9MF)

The second of the above two discrepancies assumes even more significance
in view of the following:

The Histopathologic Summary table (table 11) in Volume I of the submission
to FDA lists the following incidence of Uterine Polyps on page 87:

Incidence of Uterine Polyps

Controls Low Medium High
1 of 69 1 of 34 4 of 34 6 of 33
(1%) (3%) (12%) (18%)

The finding of one additional uterine polyp by Dr. Frith (in animal K9MF)
increases the incidence in the mid dose to 5 of 34 (15%).

On page 82 of Volume I of the submission to FDA, is the statement: "other
sporadic findings is included endometrial hyperplasia, polyp, cyst,
congestion and squamous metaplasia." The term "sporadic findings" was
used to characterize the incidence of uterine polyps, in spite of the fact
that Searle had done a statistical analysis of these findings.

(68)




The errors are tabulated below:

Wt. Shown In Wt. Recorded on
Animal No. Organ Submission Original Pathology Sheet

A12CM Kidneys 3.75 G 3.45 G
L28LM Ven. Prostrate 747 mg. 474.7 mg.
C0lMM Kidneys 9.40 G 9.219 G.
C02HM Kidneys 1.46 G 4.259 G
E14HM Kidneys 11.74 G 4.746 G
J12HM Pituitary 3.0 mg. 3.3 mg.
J30HM Ven. Prostrate 444 mg. 444.8 mg.
F17CF Ovaries 36.7 mg. 233.5 & 36.7 mg.
H30CF Liver 9.4 G 9.493 G
B20HF Uterus 1115 mg. 1155 mg.
K11HF Adrenals 799.1 mg. 797.1 mg.

(42)

[PRES. CLINTON DRINKS DIET COKE]
Heart Attack

[DICK CHENEY DRINKS DIET SPRITE]
Heart patient
Here is the short piece from Globe tabloid

CHENEY THE DIVA

VEEP'S SUITE DEMANDS

The 'suite' life of Vice President Dick Cheney included full celelebrity-style treatment in his hotel rooms while on the road. Here are some of Dick Cheney's rules; All the room lights must be turned on when he walks in and all the TV's must be tuned to the FOX news Channel. And Cheney's suite has to be kept at a chilly 68 degrees with a piping hot pot of decaffeinated coffee waiting for his arrival, according to a list of "downtime requirements" supplied by the veep's advance team to one hotel.

America's second in command also requires four--not two or six--cans of caffeine-free Diet Sprite, says the document obtained by The Smoking Gun, after a Cheney staffer gave it to a hotel employee.

When Cheney, 65, travels with his wife Lynne, 64, she needs two bottles of sparkling water, either Calistoga or the Perrier brand, according to the document.

Metabolic Disorders:
Graves Disease

Following from WOR Radio Dr. Robert Atkins Interview w/Mary Nash Stoddard:

All right, let's start taking calls you're on WOR, let's talk to Herb on Long Island.

Herb: Hello, Dr. Bob, I'd just like to relay a story about my daughter who just happened to be the first female jet pilot in the USAF. About five years ago, she came home on Thanksgiving weekend leave and she drank a lot of diet sodas. She had a bad spell here. A weak spell. But, when she got back to base, she went through a medical, and they determined that she had heart palpitations and arrhythmia.

Dr. Atkins : Were they alert to the possibility at this point in history, five years ago of diet sodas being the cause? Did they themselves think of diet sodas as the possible problem?

Herb: Yes. And, they determined that it might be the diet sodas and the artificial sweeteners.

Dr. Atkins: Mary, you should, take credit for that, I think. For giving that index of suspicion to everybody connected with caring for pilots that that is a possibility.

Mary : That's wonderful. We have done a lot of work with the FAA. Off the record, they are with us. But, on the record they can't say anything.

Herb: Also, in her group, in the Air Force, there were other pilots who were grounded because of heart problems. They discontinued using all their artificial sweeteners for one month and their flying status was restored to them. My daughter's retired now.

Dr. Atkins: Let's talk to Joy in New Jersey, Joy, you're on WOR.

Joy: Yes, good evening, Dr. Atkins and Ms. Stoddard. I experienced a severe problem with aspartame about ten years ago. I put it in my coffee. Within three minutes, I had such a headache I couldn't stand on my feet. I had palpitations and dizziness. I was deathly sick. I thought I was going to end up in the hospital.
_____________________________________________________________________________________
Statement of H. J. Roberts, M.D. Concerning Cardiac and CHEST Complaints
Attributed to Aspartame (NUTRASWEET (R))

Many patients and correspondents have asked whether products containing
aspartame can cause or aggravate symptoms relating to the heart, blood
pressure and chest. Based on my experience, as detailed in multiple
publications and books (see below), the answer is YES.

Hundreds of such instances have been documented in my database of over 950
aspartame reactors. There was dramatic improvement after avoiding
aspartame, and a prompt and predictable recurrence of these problems when
the patient resumed aspartame products ... knowingly or inadvertently.

ABNORMAL HEART RHYTHM

More than 120 individuals experienced a detectable change in their
heart rate and rhythm after consuming aspartame - including gum and
products that did not contain caffeine. This included "fluttering",
(palpitations) and rapid heart action (tachycardia). A number had even
undergone heart monitoring (Holter testing) and other studies, especially
for the associated weakness and faint.

One patient developed a slow pulse and complete heart block within hours
after consuming an aspartame drink for the first time. His attack
spontaneously subsided within a day without a pacemaker; and there has
been no recurrence.

This subject has obvious relevance to reports of unexplained sudden death
in persons who had been consuming considerable aspartame.
ATYPICAL CHEST PAIN

More than 50 aspartame reactors experienced unexplained pain in the chest.
(Many others have atypical pain elsewhere in the body). A number
underwent stress tests and coronary angioplasty for suspected coronary
heart disease; they proved normal in the majority.

SHORTNESS OF BREATH

Over 70 aspartame reactors with "shortness of breath" promptly improved
after abstaining from these prducts, and predictably suffered a recurrence
on rechallenge. Clinical sleep apnea also dramatically stopped in
these patients when they avoided aspartame.
_______________________________________________________________________

(Submitted by Mary Nash Stoddard/author Deadly Deception Story of Aspartame)
email: marystod@gmail.com

Mary Nash Stoddard
Publicist/Journalist
www.stoddardmedia.com
214.387.4001